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Ambien's Composition and Presentation

Ambien is available in tablet form, comprising the active ingredient zolpidem at a dosage of 10 milligrams. The tablets consist solely of the active substance and essential auxiliary components.

These tablets are exclusively dispensed with a prescription. Their shelf life extends to three years from the date of issuance, beyond which their utilization is advised against. It is imperative to store the medication out of reach of children, ensuring it's kept in an inaccessible location.

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Ambien's Mechanism of Action

Ambien is characterized by its sedative properties and falls within the category of imidazopyridines. It's essential to note that when taking Ambien, its sedative and benzodiazepine receptor stimulant effects should be kept in mind. This medication acts to curtail the time taken to fall asleep, diminish instances of nocturnal awakening, prolong sleep duration, and enhance its overall quality. Notably, this can lead to daytime drowsiness.

The active component of Ambien, zolpidem, is swiftly absorbed through the gastrointestinal tract, with peak concentration occurring between thirty minutes and three hours post-administration. Its bioavailability doesn't exceed 70%, while its binding to proteins reaches 92%.

Indications for the Use of Ambien

Ambien is recommended for addressing sleep disorders, specifically in cases of difficulty initiating sleep and nighttime awakenings.

Contraindications for Ambien (zolpidem) Usage

Below are the circumstances in which the administration of Ambien is contraindicated:

  • Individuals under the age of eighteen
  • Respiratory and liver failure
  • During lactation
  • Nocturnal apnea
  • Pregnancy
  • Hereditary lactose intolerance accompanied by malabsorption syndrome
  • Hypersensitivity to the drug's active substance

Exercise caution when taking Ambien for individuals with myasthenia gravis, during depressive episodes, in instances of alcoholism, drug addiction, and other dependencies.

Ambien Application and Dosage Guidelines

Ambien tablets are intended for oral administration, taken in a 10-milligram dose right before bedtime, accompanied by a small quantity of water. For elderly patients or those with impaired liver function, the medication is administered at a reduced dosage of 5 mg. It's crucial not to exceed a maximum daily dose of 10 mg. The recommended duration of the therapeutic course is up to one month.


In situations where Ambien is purchased without a prescription and an overdose occurs, the patient may experience disrupted consciousness, potentially leading to a comatose state. Additionally, a decrease in blood pressure and respiratory depression can manifest.

In the event of an overdose, it's recommended to induce vomiting within the first hour after ingestion. Subsequently, the patient should ingest several activated charcoal tablets. Furthermore, the implementation of a necessary series of symptomatic measures is advised.

Flumazenil can serve as an antidote; it functions as an antagonist to benzodiazepine receptors. It's essential to note that the use of this remedy may trigger seizures, particularly in patients with epilepsy. It's important to recognize that dialysis does not yield the desired effect in cases of Ambien overdose.

Ambien's Adverse Effects

Ambien tablets are generally well-tolerated; however, in certain instances, the occurrence of side effects is possible. These side effects can manifest in the following symptoms:

  • Drowsiness, which might be accompanied by a sense of intoxication
  • Headaches
  • Aggravated insomnia
  • Dizziness
  • Hallucinations
  • Irritability
  • Disturbing nightmares
  • Confusion
  • Aggressiveness
  • Loss of libido
  • In elderly individuals, an increased risk of frequent falls and gait disturbances

Additionally, noticeable disturbances within the digestive system may arise, often characterized by loose stools, nausea, vomiting, and abdominal pain. Furthermore, laboratory tests may reveal elevated liver enzyme activity.

Other adverse effects encompass the development of muscle weakness, potential double vision, pronounced fatigue, and skin-related issues such as itching, rashes, and excessive sweating. In some situations, angioedema, characterized by localized swelling, can also occur.

Special Precautions

When using Ambien, patients should be aware of the potential for mental and behavioral adverse effects, with a higher risk observed among elderly individuals. If such effects occur, it is advisable to temporarily discontinue the use of the medication.

In the elderly, the usage of these tablets raises the risk of significant muscle relaxation (myorelaxation) and sedation. Consequently, the medication should be prescribed with careful consideration. During the course of treatment, individuals are advised to abstain from operating vehicles or engaging in activities that require alertness.